Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22214478 | 0.77 | MAPT (0.54) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27177939 | 0.76 | ESRRG (0.78) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27177945 | 0.76 | ESRRG (0.78) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL20080851 | 0.76 | LMNA (0.72) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL21052062 | 0.76 | MAPT (0.58) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL21052063 | 0.76 | MAPT (0.58) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL14616550 | 0.76 | MAPT (0.53) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL24086403 | 0.73 | MAPT (0.50) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27178213 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL27178327 | 0.72 | SMN1; SMN2 (0.74) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087368-A2 | ANTI-CD45 ANTIBODIES AND CONJUGATES THEREOF | Magenta Therapeutics, Inc. (US) | 2021-05-06 | — | — | WO | disclosed |