SCHEMBL23333312

SCHEMBL23333312

COCc1ccc(COC2OC(C(=O)O)C(O)C(O)C2O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF2 P09038 1/20 0.46
HPSE Q9Y251 2/20 0.42
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
GLA P06280 1/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
AKT1 P31749 1/20 0.39
SLCO2B1 O94956 1/20 0.38
ABCB1 P08183 1/20 0.38
UGT1A1 P22309 1/20 0.38
HTR7 P34969 1/20 0.38
METTL3 Q86U44 1/20 0.38
ABCC2 Q92887 1/20 0.38
METTL14 Q9HCE5 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
CYP2C8 P10632 1/20 0.38
SLC5A2 P31639 2/20 0.37
ABCC1 P33527 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23333491 0.87 FGF2 (0.47) FGF2HPSEKDM4EALDH1A1HPGD
SCHEMBL7155243 0.87 FGF2 (0.49) FGF2HPSEKDM4EALDH1A1HPGD
SCHEMBL3492499 0.87 FGF2 (0.49) FGF2HPSEKDM4EALDH1A1HPGD
SCHEMBL7154155 0.85 FGF2 (0.47) FGF2HPSEKDM4EALDH1A1HPGD
SCHEMBL28576454 0.82 NT5E (0.43) FGF2ALDH1A1KMT2A
SCHEMBL13075408 0.81 CES1 (0.39) FGF2HPSEKDM4EALDH1A1HPGD
SCHEMBL18732834 0.78 TYR (0.60) KDM4EMAPK1SLC5A2POLBGAA
SCHEMBL24774074 0.78 HPSE (0.44) HPSEKDM4EALDH1A1HPGDGLA
SCHEMBL22687521 0.78 SLC6A3 (0.42) HPSEKDM4EALDH1A1HPGDGLA
SCHEMBL23333314 0.77 SLC5A2 (0.58) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021086977-A1 RAPID, HIGH-INTENSITY CHEMILUMINESCENT DIOXETANES BECKMAN COULTER, INC. (US) 2021-05-06 WO disclosed