Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 3/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13310957 | 0.83 | ALDH1A1 (0.55) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL13310979 | 0.83 | KMT2A (0.63) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL2364638 | 0.82 | KMT2A (0.62) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| Hydrochloric Acid SCHEMBL2333538 | 0.82 | KMT2A (0.65) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL2331661 | 0.82 | POLB (0.58) | S1PR2S1PR1S1PR3LPAR2KMT2A | |
| SCHEMBL13310937 | 0.81 | SMN1; SMN2 (0.70) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL2364687 | 0.79 | KMT2A (0.69) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL12445241 | 0.79 | ALDH1A1 (0.50) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| SCHEMBL2333728 | 0.78 | CYP1A2 (0.70) | KMT2AALDH1A1L3MBTL1LMNAGAA | |
| Hydrochloric Acid SCHEMBL2332778 | 0.77 | KMT2A (0.62) | KMT2AALDH1A1L3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |