SCHEMBL23337465

SCHEMBL23337465

CN1C(=O)C(NC(=O)c2nnc(Cc3ccccc3)o2)COc2cc(NN)c(N)cc21

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17312455 0.85 RIPK1 (1.00) RIPK1
SCHEMBL17312459 0.85 RIPK1 (1.00) RIPK1
SCHEMBL23337244 0.85 RIPK1 (0.77) RIPK1
SCHEMBL23337243 0.85 RIPK1 (0.77) RIPK1
SCHEMBL23337178 0.85 RIPK1 (0.75) RIPK1
SCHEMBL23337467 0.85 RIPK1 (0.75) RIPK1
SCHEMBL23336866 0.84 RIPK1 (0.74) RIPK1
SCHEMBL23336620 0.83 RIPK1 (0.73) RIPK1
SCHEMBL23336865 0.83 RIPK1 (0.73) RIPK1
SCHEMBL23336812 0.83 RIPK1 (0.73) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3816163-A1 CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) 2021-05-05 EP disclosed