⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216606 | 1.00 | — | — | |
| SCHEMBL28811422 | 0.82 | BRD4 (0.36) | — | |
| SCHEMBL19687170 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL12957658 | 0.78 | — | — | |
| SCHEMBL15641383 | 0.78 | — | — | |
| SCHEMBL2971024 | 0.77 | — | — | |
| Ethylenediamine SCHEMBL17453352 | 0.77 | ALDH1A1 (0.39) | — | |
| Ethylamine SCHEMBL28816778 | 0.77 | ALDH1A1 (0.39) | — | |
| SCHEMBL25246818 | 0.77 | ALDH1A1 (0.48) | — | |
| SCHEMBL1821223 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | claimed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| US-20210113534-A1 | COMPOUNDS | THE UNIVERSITY OF SHEFFIELD (GB) | 2021-04-22 | — | — | US | disclosed |
| WO-2020112937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| EP-2533772-A2 | METHODS AND COMPOSITIONS FOR WOUND HEALING | Wound Engineering LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100425-A2 | METHODS AND COMPOSITIONS FOR WOUND HEALING | WOUND ENGINEERING LLC (US) | 2011-08-18 | — | — | WO | disclosed |
| EP-2262474-A2 | METHODS AND COMPOSITIONS FOR WOUND HEALING | Mcanulty, Jonathan (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009097508-A2 | METHODS AND COMPOSITIONS FOR WOUND HEALING | MCANULTY, JONATHAN (US) | 2009-08-06 | — | — | WO | disclosed |
| EP-1853294-A2 | ANTI-ANGIOGENIC COMPOUNDS | Covx Technologies Ireland Limited (IE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006094269-A2 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND LIMITED (IE) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006076471-A2 | BNP CONJUGATES AND METHODS OF USE | NOBEX CORPORATION (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2002057463-A2 | SWAP/COUNTER SELECTION; A RAPID CLONING METHOD | GALAPAGOS GENOMICS B.V. (NL) | 2002-07-25 | — | — | WO | disclosed |
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | disclosed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |