Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | HRH1 | P35367 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12124778 | 1.00 | TMEM97 (1.00) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL1325469 | 1.00 | TMEM97 (1.00) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL1325413 | 1.00 | TMEM97 (1.00) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL29860557 | 1.00 | TMEM97 (1.00) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL29781243 | 0.99 | TMEM97 (0.98) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1325448 | 0.99 | TMEM97 (0.98) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL12124588 | 0.88 | TMEM97 (0.79) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL16216949 | 0.88 | SIGMAR1 (0.87) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL12359945 | 0.88 | SIGMAR1 (0.87) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL12124623 | 0.88 | TMEM97 (0.79) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102204-B1 | HIGHLY SELECTIVE SIGMA 1 RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHOPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE UNIV OF MISSISSIPPI (US) | 2021-05-05 | — | — | EP | disclosed |