Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23339263 | 0.80 | SIGMAR1 (0.52) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL23339727 | 0.72 | ABCB1 (0.47) | SIGMAR1TMEM97ABCB1GRIN1GRIN2B | |
| SCHEMBL23339232 | 0.70 | ABCB1 (0.47) | SIGMAR1TMEM97ABCB1GRIN1GRIN2B | |
| SCHEMBL23339240 | 0.68 | SIGMAR1 (0.43) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL7632636 | 0.66 | SMN1; SMN2 (0.41) | SIGMAR1 | |
| SCHEMBL5757125 | 0.65 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL2330002 | 0.65 | SIGMAR1 (0.67) | SIGMAR1TMEM97ABCB1 | |
| SCHEMBL23339303 | 0.65 | SIGMAR1 (0.44) | SIGMAR1TMEM97ABCB1GRIN1GRIN2B | |
| SCHEMBL6656817 | 0.65 | SIGMAR1 (0.57) | SIGMAR1TMEM97ABCB1GRIN1GRIN2B | |
| SCHEMBL6659238 | 0.65 | SIGMAR1 (0.61) | SIGMAR1TMEM97ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102204-B1 | HIGHLY SELECTIVE SIGMA 1 RECEPTOR LIGANDS AND RADIOLIGANDS AS PROBES IN NOCICEPTIVE PROCESSING AND THE PATHOPHYSIOLOGICAL STUDY OF MEMORY DEFICITS AND COGNITIVE DISORDERS | THE UNIV OF MISSISSIPPI (US) | 2021-05-05 | — | — | EP | disclosed |