Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 7/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340498 | 0.94 | NUDT5 (0.48) | NUDT5PLK1TLR8TLR7LMNA | |
| SCHEMBL23340703 | 0.90 | NUDT5 (0.38) | NUDT5PLK1LMNAHPGDTSHR | |
| SCHEMBL23340325 | 0.90 | NUDT5 (0.54) | NUDT5PLK1TLR8TLR7LMNA | |
| SCHEMBL23340638 | 0.89 | NUDT5 (0.36) | NUDT5PLK1TLR8TLR7LMNA | |
| SCHEMBL23340701 | 0.89 | NUDT5 (0.36) | NUDT5PLK1LMNAHPGDTSHR | |
| SCHEMBL23340643 | 0.89 | NUDT5 (0.37) | NUDT5PLK1TLR8TLR7LMNA | |
| SCHEMBL23340461 | 0.88 | NUDT5 (0.46) | NUDT5PLK1LMNAHTR2CTSHR | |
| SCHEMBL23340704 | 0.88 | NUDT5 (0.56) | NUDT5PLK1TLR8TLR7HTR2C | |
| SCHEMBL23340555 | 0.88 | HPGD (0.44) | NUDT5TLR8TLR7LMNAHPGD | |
| SCHEMBL23340636 | 0.87 | NUDT5 (0.46) | NUDT5HTR2CTSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | ADORA2A, HPRT1, PNP | NUDT5 105/4885PLK1 2110/4885TLR8 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.