Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 7/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340325 | 0.89 | NUDT5 (0.54) | NUDT5HTR2CPLK1TLR9TLR8 | |
| SCHEMBL23340556 | 0.88 | NUDT5 (0.47) | NUDT5HTR2CMAPTPLK1TLR9 | |
| SCHEMBL23340639 | 0.86 | NUDT5 (0.47) | NUDT5HTR2CMAPTSOS1RAB9A | |
| SCHEMBL23340553 | 0.86 | NUDT5 (0.47) | NUDT5HTR2CMAPTDPP4RAB9A | |
| SCHEMBL23340498 | 0.86 | NUDT5 (0.48) | NUDT5MAPTPLK1POLBTLR9 | |
| SCHEMBL23340497 | 0.85 | NUDT5 (0.47) | NUDT5HTR2CMAPTDPP4RAB9A | |
| SCHEMBL23340637 | 0.85 | NUDT5 (0.47) | NUDT5HTR2CMAPTRAB9A | |
| SCHEMBL23340461 | 0.85 | NUDT5 (0.46) | NUDT5HTR2CMAPTPLK1 | |
| SCHEMBL23340617 | 0.85 | NUDT5 (0.52) | NUDT5RAB9ATLR8TLR7 | |
| SCHEMBL23340335 | 0.84 | NUDT5 (0.46) | NUDT5HTR2CMAPTSOS1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | ADORA2A, HPRT1, PNP | NUDT5 105/4885HTR2C 1202/4885MAPT 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.