Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 15/20 | 0.67 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.67 |
| ▸ | SYK | P43405 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14657468 | 1.00 | MAPK8 (0.67) | MAPK8MAPK9SYK | |
| SCHEMBL28454476 | 0.91 | MAPK8 (0.57) | MAPK8MAPK9SYK | |
| SCHEMBL14656638 | 0.90 | MAPK8 (0.54) | MAPK8MAPK9SYK | |
| SCHEMBL23340833 | 0.87 | SYK (0.58) | MAPK8SYK | |
| SCHEMBL14657553 | 0.87 | MAPK8 (0.69) | MAPK8MAPK9SYK | |
| SCHEMBL15249749 | 0.85 | SYK (0.65) | MAPK8SYK | |
| SCHEMBL28416204 | 0.84 | MAPK8 (0.51) | MAPK8MAPK9SYK | |
| SCHEMBL14657356 | 0.84 | JAK1 (0.59) | MAPK8MAPK9SYK | |
| SCHEMBL30873297 | 0.84 | JAK1 (0.59) | MAPK8MAPK9SYK | |
| SCHEMBL14671124 | 0.83 | MAPK8 (0.73) | MAPK8MAPK9SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3497103-B1 | PYRIDOPYRIMDINONE CDK2/4/6 INHIBITORS | PFIZER (US) | 2021-05-05 | — | — | EP | disclosed |