Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 15/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.57 |
| ▸ | SYK | P43405 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13735160 | 0.92 | MAPK8 (0.66) | MAPK8MAPK9SYK | |
| SCHEMBL23340803 | 0.91 | MAPK8 (0.67) | MAPK8MAPK9SYK | |
| SCHEMBL14657468 | 0.91 | MAPK8 (0.67) | MAPK8MAPK9SYK | |
| SCHEMBL28449158 | 0.83 | MAPK8 (0.62) | MAPK8MAPK9SYK | |
| SCHEMBL14656638 | 0.82 | MAPK8 (0.54) | MAPK8MAPK9SYK | |
| SCHEMBL28455414 | 0.81 | MAPK8 (0.37) | MAPK8MAPK9 | |
| SCHEMBL2385046 | 0.80 | SYK (0.60) | MAPK8SYK | |
| SCHEMBL13736959 | 0.80 | MAPK8 (0.68) | MAPK8MAPK9SYK | |
| SCHEMBL23340833 | 0.79 | SYK (0.58) | MAPK8SYK | |
| SCHEMBL28453682 | 0.79 | MAPK8 (0.60) | MAPK8MAPK9SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471021-A | Substituted diaminocarboxamides and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith | 西格诺药品有限公司 | 2020-07-31 | — | — | CN | disclosed |