Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958435 | 0.79 | CSNK2A1 (0.41) | SLC22A12HTTMAPTHPGDALDH1A1 | |
| SCHEMBL20738269 | 0.76 | CYP1A1 (0.45) | MAPTHPGDALDH1A1CYP1A2KDM4E | |
| SCHEMBL29704576 | 0.73 | CYP1A2 (0.64) | HTTMAPTHPGDALDH1A1HSP90AA1 | |
| SCHEMBL20150978 | 0.73 | SLC22A12 (0.39) | SLC22A12HTTMAPTHPGDALDH1A1 | |
| SCHEMBL8764187 | 0.73 | CYP1A2 (0.42) | HTTMAPTHPGDALDH1A1HSP90AA1 | |
| SCHEMBL5752787 | 0.71 | RXFP1 (0.41) | SLC22A12HTTMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9314804 | 0.71 | MAPT (0.39) | SLC22A12HTTMAPTALDH1A1KDM4E | |
| SCHEMBL29842323 | 0.71 | SLC22A12 (0.38) | SLC22A12HTTMAPTALDH1A1KDM4E | |
| SCHEMBL1229310 | 0.71 | SLC22A12 (0.38) | SLC22A12HTTMAPTALDH1A1KDM4E | |
| SCHEMBL31281348 | 0.71 | RXFP1 (0.41) | SLC22A12HTTMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3480188-B1 | METHOD FOR PREPARING URATE TRANSPORTER 1 INHIBITOR | TIANJIN INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |