Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466440 | 0.87 | L3MBTL1 (0.44) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL29558862 | 0.87 | L3MBTL1 (0.44) | MAPTKMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL9313596 | 0.86 | PARP1 (0.41) | KMT2AMEN1LMNAALDH1A1TSHR | |
| SCHEMBL1229310 | 0.81 | SLC22A12 (0.38) | MAPTSMN1; SMN2KDM4EHTTNPBWR1 | |
| SCHEMBL31281348 | 0.81 | RXFP1 (0.41) | MAPTSMN1; SMN2KDM4EHTTSLC22A12 | |
| SCHEMBL5752787 | 0.81 | RXFP1 (0.41) | MAPTSMN1; SMN2KDM4EHTTSLC22A12 | |
| SCHEMBL29842323 | 0.81 | SLC22A12 (0.38) | MAPTSMN1; SMN2KDM4EHTTNPBWR1 | |
| SCHEMBL1856186 | 0.79 | LOXL2 (0.45) | MAPTSMN1; SMN2KDM4EHTTSLC22A12 | |
| SCHEMBL31596398 | 0.79 | LMNA (0.45) | MAPTSMN1; SMN2KDM4EHTTNPBWR1 | |
| SCHEMBL11893022 | 0.79 | LMNA (0.45) | MAPTSMN1; SMN2KDM4EHTTNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430548-A | Preparation method of URAT1 inhibitor intermediate | 浙江博崤生物制药有限公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2020067594-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | 희성소재(주) | 2020-04-02 | — | — | WO | disclosed |
| CN-1051702-C | Preparing process of amine derivative and fungusicide containing amine derivative | SCIENT RESEARCH AND PHARMACEUT (JP) | 2000-04-26 | — | — | CN | disclosed |
| US-RE34770-E | 1-benzothiophene derivatives; side effect reduction | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| US-5334628-A | Amine derivatives, processes for preparing the same and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |
| US-5200423-A | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5106866-A | Skin disorders | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021458-A | Amine derivatives and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0164697-B1 | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-11-07 | — | — | EP | disclosed |
| CN-1007975-B | Process for the preparation of amine derivatives | KAKEN PHARMACEUFICAL CO LTD (JP) | 1990-05-16 | — | — | CN | disclosed |
| CN-1035771-A | Process for the preparation of amine derivatives and fungicides containing amine derivatives | SCIENT RESEARCH AND PHARMACEUT (JP) | 1989-09-27 | — | — | CN | disclosed |
| CN-85104330-A | Process for the preparation of amine derivatives and fungicides containing amine derivatives | — | 1986-12-03 | — | — | CN | disclosed |
| EP-0164697-A2 | Amine derivatives, processes for preparing the same and fungicides containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |