SCHEMBL2334148

SCHEMBL2334148

CCCOC(=O)[C@H](CCSC)NC(=O)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.52
CNR2 P34972 2/20 0.50
FNTA P49354 2/20 0.47
FNTB P49356 2/20 0.47
PGGT1B P53609 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
ANPEP P15144 1/20 0.46
PPID Q08752 1/20 0.45
LTA4H P09960 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2334144 1.00 POLB (0.52) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2330757 0.90 PPID (0.55) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2330760 0.90 PPID (0.55) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2328031 0.87 L3MBTL1 (0.56) POLBFNTAFNTBPGGT1BL3MBTL1
SCHEMBL2328029 0.87 L3MBTL1 (0.56) POLBFNTAFNTBPGGT1BL3MBTL1
SCHEMBL4422071 0.85 POLB (0.52) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL6136477 0.85 POLB (0.52) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2331099 0.83 FNTA (0.61) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2331097 0.83 FNTA (0.61) POLBCNR2FNTAFNTBPGGT1B
SCHEMBL2328066 0.83 POLB (0.51) POLBCNR2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
CN-102215812-B Anti-wrinkle agents POLA CHEM IND INC 2014-09-10 CN disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 POLB 1044/4885CNR2 1779/4885FNTA 4644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.