SCHEMBL2334174

SCHEMBL2334174

COc1ccc(C(CCOC(N)=O)N2CCC(CNC(=O)n3c(=O)n(C(C)C)c4ccccc43)CC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2341151 0.92 HTR4 (0.55) HTR4
SCHEMBL2336910 0.92 HTR4 (0.54) HTR4
SCHEMBL2333567 0.89 HTR4 (0.45) HTR4
SCHEMBL2335422 0.84 HTR4 (0.53) HTR4
SCHEMBL15103613 0.82 HTR4 (0.54) HTR4
SCHEMBL2338920 0.81 HTR4 (0.55) HTR4
SCHEMBL2334884 0.81 HTR4 (0.46) HTR4
SCHEMBL2334262 0.80 HTR4 (0.58) HTR4
SCHEMBL2338629 0.80 HTR4 (0.44) HTR4
SCHEMBL3301067 0.78 HTR4 (0.54) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358702-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK Holdings Co., Ltd. (KR) 2011-08-24 EP claimed
WO-2010044585-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK HOLDINGS CO., LTD. (KR) 2010-04-22 WO claimed
EP-2358702-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK Holdings Co., Ltd. (KR) 2011-08-24 EP disclosed
WO-2010044585-A2 PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE SK HOLDINGS CO., LTD. (KR) 2010-04-22 WO disclosed