Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | SUCNR1 | Q9BXA5 | 8/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938796 | 0.85 | TDP1 (0.40) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL911292 | 0.83 | CA1 (0.53) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL910120 | 0.82 | CA1 (0.54) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL16572363 | 0.80 | CA12 (0.50) | CA1CA2CA12CA9 | |
| SCHEMBL16627553 | 0.80 | CA1 (0.53) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL911229 | 0.80 | CA12 (0.49) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL16498852 | 0.79 | CA1 (0.50) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL23291248 | 0.79 | CA1 (0.51) | CA1CA2CA12CA9 | |
| SCHEMBL910742 | 0.79 | CA1 (0.55) | CA1CA2CA12CA9SUCNR1 | |
| SCHEMBL5015557 | 0.78 | CA1 (0.59) | CA1CA2CA12CA9SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485360-B1 | SODIUM CHANNEL BLOCKERS | PARION SCIENCES INC (US) | 2011-08-17 | — | — | EP | disclosed |