SCHEMBL23344642

SCHEMBL23344642

CCCCC(NC)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
KMT2A Q03164 4/20 0.43
CYP1A2 P05177 3/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP26A1 O43174 1/20 0.39
MEN1 O00255 3/20 0.38
HPGD P15428 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
ATM Q13315 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20033655 0.84 ALDH1A1 (0.50) ALDH1A1KMT2ACYP1A2TSHRCYP3A4
SCHEMBL10400828 0.80 ALDH1A1 (0.49) ALDH1A1KMT2ACYP1A2TSHRCYP3A4
SCHEMBL6680574 0.80 ALDH1A1 (0.45) ALDH1A1KMT2ACYP1A2TSHRHSD17B10
SCHEMBL28488604 0.79 ALDH1A1 (0.44) ALDH1A1KMT2ACYP1A2TSHRHSD17B10
SCHEMBL620127 0.78 ALDH1A1 (0.47) ALDH1A1KMT2ACYP1A2TSHRCYP3A4
SCHEMBL3107386 0.76 KMT2A (0.48) ALDH1A1KMT2ACYP1A2TSHRMEN1
SCHEMBL1123533 0.76 ALDH1A1 (0.48) ALDH1A1KMT2ACYP1A2TSHRCYP3A4
SCHEMBL29116460 0.76 CYSLTR2 (0.45) ALDH1A1KMT2ACYP1A2TSHRHSD17B10
SCHEMBL6683965 0.76 ALDH1A1 (0.44) ALDH1A1KMT2ACYP1A2TSHRHSD17B10
SCHEMBL3969391 0.75 CYP1A2 (0.65) ALDH1A1KMT2ACYP1A2TSHRCYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3207374-B1 METHOD AND SYSTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A FLUID SAMPLE LABCYTE INC (US) 2021-05-12 EP disclosed