⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22389250 | 0.87 | — | — | |
| SCHEMBL23344665 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL21316726 | 0.75 | MEN1 (0.41) | — | |
| SCHEMBL409344 | 0.70 | — | — | |
| SCHEMBL15443892 | 0.70 | TSHR (0.30) | — | |
| SCHEMBL409726 | 0.69 | — | — | |
| SCHEMBL409233 | 0.67 | L3MBTL3 (0.30) | — | |
| SCHEMBL409244 | 0.67 | — | — | |
| SCHEMBL20251116 | 0.67 | — | — | |
| SCHEMBL18993493 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139897-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | SAREPTA THERAPEUTICS, INC. | 2021-05-13 | — | — | US | disclosed |