Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23345082 | 0.96 | SOS1 (0.74) | SOS1 | |
| SCHEMBL23345044 | 0.93 | SOS1 (0.71) | SOS1 | |
| SCHEMBL23345040 | 0.92 | SOS1 (0.79) | SOS1 | |
| SCHEMBL23995785 | 0.89 | SOS1 (0.68) | SOS1 | |
| SCHEMBL23344893 | 0.89 | SOS1 (0.81) | SOS1 | |
| SCHEMBL23326320 | 0.88 | SOS1 (0.81) | SOS1 | |
| SCHEMBL29861247 | 0.88 | SOS1 (0.81) | SOS1 | |
| SCHEMBL23326318 | 0.88 | SOS1 (0.81) | SOS1 | |
| SCHEMBL23345260 | 0.88 | SOS1 (0.70) | SOS1 | |
| SCHEMBL23345114 | 0.87 | SOS1 (1.00) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | SOST, SOS1, SOS2 | SOS1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.