Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015828 | 0.83 | BCL2 (0.46) | PTGS2HTR7HTR1APTGS1PRMT5 | |
| SCHEMBL7611761 | 0.82 | MEN1 (0.53) | ALDH1A1LMNAKMT2ACDK8 | |
| Hydrochloric Acid SCHEMBL6427782 | 0.81 | KMT2A (0.55) | ALDH1A1LMNAKMT2ACDK8 | |
| SCHEMBL23296176 | 0.80 | GAA (0.52) | ALDH1A1KMO | |
| SCHEMBL18014715 | 0.79 | PTGS2 (0.41) | PTGS2HTR7HTR1APTGS1PRMT5 | |
| SCHEMBL12326172 | 0.77 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1KMT2AADORA2A | |
| SCHEMBL29375895 | 0.76 | ADORA2A (0.55) | PTGS2PTGS1ALDH1A1LMNAKMT2A | |
| SCHEMBL403698 | 0.76 | ADORA2A (0.55) | PTGS2PTGS1ALDH1A1LMNAKMT2A | |
| SCHEMBL5182530 | 0.74 | PTGS2 (0.42) | PTGS2PTGS1PRMT5WDR77ALDH1A1 | |
| SCHEMBL9617394 | 0.74 | CYP17A1 (0.49) | PTGS2PTGS1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819006-A1 | COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-12 | — | — | EP | disclosed |