⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933294 | 0.75 | — | — | |
| SCHEMBL1815629 | 0.73 | — | — | |
| SCHEMBL856758 | 0.64 | — | — | |
| SCHEMBL20660050 | 0.64 | — | — | |
| SCHEMBL2020527 | 0.61 | CYP2D6 (0.30) | — | |
| SCHEMBL5196121 | 0.61 | — | — | |
| SCHEMBL28570455 | 0.60 | — | — | |
| SCHEMBL6573328 | 0.57 | — | — | |
| SCHEMBL3541133 | 0.57 | — | — | |
| SCHEMBL5521713 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2940009-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VentiRx Pharmaceuticals, Inc. (US) | 2015-11-04 | — | — | EP | claimed |
| EP-2358683-B1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS INC (US) | 2015-04-01 | — | — | EP | claimed |
| US-8314090-B2 | Methods of synthesis of benzazepine derivatives | VENTIRX PHARMACEUTICALS, INC. (US) | 2012-11-20 | — | — | US | claimed |
| EP-2358683-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | Ventirx Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | claimed |
| US-20100216989-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | claimed |
| WO-2010054215-A1 | METHODS OF SYNTHESIS OF BENZAZEPINE DERIVATIVES | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | claimed |