Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15515566 | 0.84 | HPGD (0.56) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL8959651 | 0.81 | EIF4A3 (0.54) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL27530562 | 0.81 | HPGD (0.53) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL30310477 | 0.75 | EIF4A3 (0.61) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL3605104 | 0.75 | HPGD (0.53) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL7677228 | 0.75 | EIF4A3 (0.61) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL1144741 | 0.74 | HPGD (0.60) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL16428858 | 0.71 | HPGD (0.57) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL4073035 | 0.71 | HPGD (0.49) | HPGDHSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL3094576 | 0.70 | HSD17B10 (0.56) | HPGDHSD17B10ALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377482-B1 | MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS LLC (US) | 2021-05-12 | — | — | EP | disclosed |