Sugi Predict

Sugi Predict / Compounds / SCHEMBL4073035

SCHEMBL4073035

SCHEMBL4073035

O=C(O)c1cc2ccnc(Cl)c2[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.49
▸ HSD17B10 Q99714 3/20 0.49
▸ ALDH1A1 P00352 3/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ USP2 O75604 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ CCNC P24863 1/20 0.47
▸ CDK8 P49336 1/20 0.47
▸ HASPIN Q8TF76 1/20 0.47
▸ F7 P08709 1/20 0.46
▸ F3 P13726 1/20 0.46
▸ APEX1 P27695 2/20 0.44
▸ EIF4A3 P38919 1/20 0.43
▸ DAO P14920 3/20 0.42
▸ KDM4E B2RXH2 3/20 0.42
▸ MAPT P10636 1/20 0.42
▸ SRD5A2 P31213 1/20 0.42
▸ SYK P43405 1/20 0.41
▸ SMAD3 P84022 1/20 0.40
▸ LMNA P02545 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25581554 0.85 RXFP1 (0.40) HPGDHSD17B10ALDH1A1MEN1USP2
SCHEMBL4271295 0.83 KMT2A (0.52) HPGDHSD17B10ALDH1A1MEN1USP2
SCHEMBL20504460 0.81 XDH (0.47) MAPTSYK
SCHEMBL1569014 0.80 HPGD (0.49) HPGDHSD17B10ALDH1A1MEN1USP2
SCHEMBL4278472 0.80 NSD2 (0.59) MAPTLMNASMN1; SMN2
SCHEMBL4268287 0.78 MAPT (0.60) MAPTLMNAKDM4C
SCHEMBL29942182 0.78 CDK1 (0.55) HPGDHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL30220550 0.78 ALOX15 (0.54) CCNCCDK8HASPINMAPTLMNA
SCHEMBL30122360 0.77 CDK1 (0.54) HPGDHSD17B10ALDH1A1MEN1KMT2A
SCHEMBL4275837 0.77 KMT2A (0.48) MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370207-B1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2025-12-17 — — EP disclosed
US-20240368137-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2024-11-07 — — US disclosed
US-20240228504-A1 SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-11 — — US disclosed
US-20240228504-A1 SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-11 — — US disclosed
US-12012398-B2 Bicyclic compounds as androgen receptor modulators NIDO BIOSCIENCES, INC. (US) 2024-06-18 — — US disclosed
EP-4370207-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS Nido Biosciences, Inc. (US) 2024-05-22 — — EP disclosed
EP-4149945-A1 SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME Arbutus Biopharma Corporation (CA) 2023-03-22 — — EP disclosed
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-09 — — US disclosed
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2023-02-09 — — US disclosed
WO-2023287704-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2023-01-19 — — WO disclosed
US-7608627-B2 I kappa B kinase inhibition; diabetes; (7-Chloro-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol; N-Benzyl-7-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-10-27 — — US disclosed
US-20090099176-A1 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES PROSIDION LIMITED (GB) 2009-04-16 — — US disclosed
EP-1819332-B1 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES PROSIDION LTD (GB) 2009-03-11 — — EP disclosed
US-20080064715-A1 6-Azaindole Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-03-13 — — US disclosed
EP-1819332-A2 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES Prosidion Limited (GB) 2007-08-22 — — EP disclosed
CN-1330307-C Indole, azaindole and related heterocyclic amidopiperazine derivatives BRISTOL MYERS SQUIBB CO LTD (US) 2007-08-08 — — CN disclosed
EP-1732566-A2 6-AZAINDOLE COMPOUND Takeda Pharmaceutical Company Limited (JP) 2006-12-20 — — EP disclosed
WO-2006059164-A2 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES PROSIDION LIMITED (GB) 2006-06-08 — — WO disclosed
WO-2005097129-A2 6-AZAINDOLE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-10-20 — — WO disclosed
CN-1520295-A Indole, azaindole and related heterocyclic amidopiperazine derivatives ����˹�ж�-����˹˹������˾ 2004-08-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230039586-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HPGD 1466/4885HSD17B10 73/4885ALDH1A1 2558/4885
US-20090099176-A1 PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDES PC, GOT2, PDK1 HPGD 120/4885HSD17B10 195/4885ALDH1A1 397/4885
US-20240228504-A1 SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME SLC10A1, NR1H4, SLC10A2 HPGD 808/4885HSD17B10 237/4885ALDH1A1 3140/4885
US-20240368137-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NR5A1 HPGD 1466/4885HSD17B10 73/4885ALDH1A1 2558/4885
US-12012398-B2 Bicyclic compounds as androgen receptor modulators AR, FSHR, NCOA3 HPGD 1635/4885HSD17B10 83/4885ALDH1A1 2865/4885
US-20080064715-A1 6-Azaindole Compound RELA, NFKBIA, GPR119 HPGD 3042/4885HSD17B10 3742/4885ALDH1A1 3508/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.