Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 1.00 |
| ▸ | HTR2C | P28335 | 6/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | HTR1D | P28221 | 1/20 | 0.67 |
| ▸ | HTR1E | P28566 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.67 |
| ▸ | HTR7 | P34969 | 1/20 | 0.67 |
| ▸ | HTR6 | P50406 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455136 | 1.00 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL23348160 | 1.00 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL16446269 | 0.99 | HTR2A (0.97) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL23326091 | 0.99 | HTR2A (0.97) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL29775411 | 0.99 | HTR2A (0.97) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL29775373 | 0.99 | HTR2A (0.97) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL23326140 | 0.99 | HTR2A (0.97) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| SCHEMBL4891707 | 0.83 | HTR2A (0.71) | HTR2AHTR2CHTR2BHTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL4728095 | 0.82 | HTR2A (0.70) | HTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL23348061 | 0.80 | HTR2A (1.00) | HTR2AHTR2CHTR2BHTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11642336-B2 | 5-HT2A agonists for use in treatment of depression | Lophora ApS (DK) | 2023-05-09 | — | — | US | disclosed |
| US-11642336-B2 | 5-HT2A agonists for use in treatment of depression | Lophora ApS (DK) | 2023-05-09 | — | — | US | disclosed |
| US-11246860-B2 | 5-HT2A agonists for use in treatment of depression | Lophora ApS (DK) | 2022-02-15 | — | — | US | disclosed |
| US-20210330658-A1 | 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION | Lophora ApS (DK) | 2021-10-28 | — | — | US | disclosed |
| US-20210137908-A1 | 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION | Lophora ApS (DK) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330658-A1 | 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION | HTR2A, HTR2C, HTR5A | HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885 |
| US-11642336-B2 | 5-HT2A agonists for use in treatment of depression | HTR2A, HTR2C, HTR5A | HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885 |
| US-20210137908-A1 | 5-HT2A AGONISTS FOR USE IN TREATMENT OF DEPRESSION | HTR2A, HTR2C, HTR5A | HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885 |
| US-11246860-B2 | 5-HT2A agonists for use in treatment of depression | HTR2A, HTR2C, HTR5A | HTR2A 1/4885HTR2C 2/4885HTR2B 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.