Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23348311 | 0.90 | CYP11B1 (0.36) | KDM5BCYP11B1CYP11B2KDM4AESR1 | |
| SCHEMBL23348303 | 0.90 | KDM5B (0.34) | KDM5BCYP11B1CYP11B2KDM4AESR1 | |
| SCHEMBL22250449 | 0.87 | GRIA4 (0.36) | CYP11B1CYP11B2ADORA1ADORA2AALDH1A1 | |
| SCHEMBL16127446 | 0.85 | KDM5B (0.40) | KDM5BCYP11B1CYP11B2KDM4AESR1 | |
| SCHEMBL29581709 | 0.85 | ADORA1 (0.39) | KDM5BCYP11B1CYP11B2KDM4ATSPO | |
| SCHEMBL16176005 | 0.85 | ADORA1 (0.39) | KDM5BCYP11B1CYP11B2KDM4ATSPO | |
| SCHEMBL29380865 | 0.85 | ADORA1 (0.39) | KDM5BCYP11B1CYP11B2KDM4ATSPO | |
| SCHEMBL17570521 | 0.85 | ADORA1 (0.39) | KDM5BCYP11B1CYP11B2KDM4ATSPO | |
| SCHEMBL23348308 | 0.85 | KDM5B (0.34) | KDM5BCYP11B1CYP11B2KDM4AESR1 | |
| SCHEMBL22251509 | 0.85 | GRIA4 (0.35) | KDM5BCYP11B1CYP11B2ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139425-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CCND2, CCND1, CRY1 | KDM5B 3881/4885CYP11B1 1671/4885CYP11B2 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.