Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18626181 | 0.86 | FFAR1 (0.43) | GRM5FFAR1FFAR4TSPODRD3 | |
| SCHEMBL18626182 | 0.84 | CYP11B1 (0.45) | GRM5FFAR1FFAR4TSPODRD3 | |
| SCHEMBL18626194 | 0.82 | CYP1A1 (0.40) | GRM5FFAR1FFAR4TSPODRD3 | |
| SCHEMBL21675422 | 0.81 | GRM5 (0.42) | GRM5FFAR1FFAR4TSPODRD3 | |
| SCHEMBL20749389 | 0.78 | ALDH1A1 (0.38) | GRM5FFAR1FFAR4CA12CA2 | |
| SCHEMBL20228244 | 0.77 | CYP11B1 (0.39) | FFAR1FFAR4 | |
| SCHEMBL18842350 | 0.76 | GRM5 (0.40) | GRM5FFAR1FFAR4TSPODRD3 | |
| SCHEMBL20228301 | 0.75 | ALDH1A1 (0.35) | GRM5FFAR1FFAR4CA12CA2 | |
| SCHEMBL22622676 | 0.73 | SCN5A (0.35) | CA12CA9 | |
| SCHEMBL24296671 | 0.72 | FFAR1 (0.37) | FFAR1FFAR4TSPODRD3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3599266-B1 | LIQUID-CRYSTAL LENS | MERCK PATENT GMBH (DE) | 2021-05-12 | — | — | EP | disclosed |