Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23253904 | 0.73 | ESR2 (0.54) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL38653719 | 0.73 | ESR2 (0.54) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL3328949 | 0.72 | HDAC1 (0.44) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL4585780 | 0.70 | TMEM97 (0.43) | HDAC1DDB1CRBNESR2MAPK1 | |
| SCHEMBL28892610 | 0.68 | ESR2 (0.51) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL28863446 | 0.67 | HDAC1 (0.48) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL3876205 | 0.67 | DDB1 (0.58) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL4247895 | 0.67 | PDK2 (0.52) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL5183098 | 0.67 | MAPK1 (0.64) | HDAC1DDB1CRBNESR2NR1H2 | |
| SCHEMBL29676965 | 0.67 | MAPK1 (0.64) | HDAC1DDB1CRBNESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358736-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | Intermune, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |