Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509608 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL7428953 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL5074242 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL4757619 | 0.73 | GAA (0.53) | SMN1; SMN2GAAALDH1A1TDP1KDM4E | |
| SCHEMBL5707155 | 0.73 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL274448 | 0.71 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL14421937 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL13116870 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 | |
| SCHEMBL7358278 | 0.71 | GAA (0.57) | SMN1; SMN2GAAALDH1A1TDP1KDM4E | |
| SCHEMBL11039671 | 0.71 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819298-A1 | COMPOUND HAVING TRKA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR ALLEVIATING PAIN, CONTAINING SAME AS ACTIVE INGREDIENT | Oncopharmatech Inc. (KR) | 2021-05-12 | — | — | EP | disclosed |