Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274448 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAALDH1A1CHRM1POLB | |
| Hydrochloric Acid SCHEMBL4788803 | 0.98 | SMN1; SMN2 (0.57) | SMN1; SMN2GAAALDH1A1CHRM1POLB | |
| Hydrochloric Acid SCHEMBL14311961 | 0.98 | SMN1; SMN2 (0.57) | SMN1; SMN2GAAALDH1A1CHRM1POLB | |
| Oxalic Acid SCHEMBL23497895 | 0.93 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAALDH1A1CHRM1TDP1 | |
| SCHEMBL16377760 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL13964802 | 0.88 | CHRM1 (0.59) | SMN1; SMN2GAAALDH1A1CHRM1MEN1 | |
| SCHEMBL12457873 | 0.86 | — | — | |
| SCHEMBL2743262 | 0.86 | — | — | |
| SCHEMBL13748108 | 0.86 | — | — | |
| SCHEMBL26095936 | 0.82 | ALDH1A1 (0.56) | SMN1; SMN2GAAALDH1A1CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428935-A | BETA-LACTAMASE INHIBITORS | PFIZER INC. (US) | 1984-01-31 | — | — | US | claimed |