Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28712800 | 1.00 | LMNA (0.48) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Succinic Acid SCHEMBL10897257 | 1.00 | LMNA (0.48) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Succinic Acid SCHEMBL231928 | 1.00 | LMNA (0.48) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Adipic Acid SCHEMBL10772168 | 0.91 | ABCC4 (0.48) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Adipic Acid SCHEMBL38651009 | 0.91 | ABCC4 (0.48) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL2783417 | 0.90 | LMNA (0.59) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL9847746 | 0.90 | LMNA (0.59) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL151893 | 0.90 | LMNA (0.59) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL14762290 | 0.90 | LMNA (0.59) | LMNAMAPK1ALDH1A1TP53CYP3A4 | |
| Acrylic Acid SCHEMBL4623894 | 0.90 | LMNA (0.59) | LMNAMAPK1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218244-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-04 | — | — | US | disclosed |
| WO-2024111420-A1 | ALKALI-SOLUBLE RESIN, LIGHT-SENSITIVE RESIN COMPOSITION, METHODS RESPECTIVELY FOR PRODUCING THOSE, AND USE OF THOSE | 株式会社日本触媒 | 2024-05-30 | — | — | WO | disclosed |
| US-20240166791-A1 | CURED FILM AND DISPLAY DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-05-23 | — | — | US | disclosed |
| WO-2024084904-A1 | CURABLE COMPOSITION, CURED FILM, AND DISPLAY DEVICE | 住友化学株式会社 | 2024-04-25 | — | — | WO | disclosed |
| WO-2024053609-A1 | ALKALI-SOLUBLE RESIN, METHOD FOR PRODUCING SAME, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, MEMBER FOR DISPLAY DEVICE, AND DISPLAY DEVICE | 株式会社日本触媒 | 2024-03-14 | — | — | WO | disclosed |
| EP-4332123-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| EP-4332122-A1 | CURED FILM AND DISPLAY DEVICE | Sumitomo Chemical Company, Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023248976-A1 | POLYMER AND METHOD FOR PRODUCING SAME, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, AND MONOMER COMPOUND AND METHOD FOR PRODUCING SAME | 株式会社日本触媒 | 2023-12-28 | — | — | WO | disclosed |
| WO-2023218876-A1 | ALKALI-SOLUBLE RESIN, PHOTOSENSITIVE RESIN COMPOSITION, AND CURED PRODUCT THEREOF | 株式会社日本触媒 | 2023-11-16 | — | — | WO | disclosed |
| US-20230340289-A1 | PHOTOSENSITIVE COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-10-26 | — | — | US | disclosed |
| EP-2169463-A2 | Colored curable composition, color filter and method for producing the same | FUJIFILM Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2112182-A1 | Polymerizable composition, light-shielding color filter, black curable composition, light-shielding color filter for solid-state image pickup device and method of producing the same, and solid-state image pickup device | FUJIFILM Corporation (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20090117330-A1 | ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR MANUFACTURING EMBOSSED RELEASE SHEET, APPARATUS FOR MANUFACTURING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR MANUFACTURING SYNTHETIC LEATHER | DAI NIPPON PRINTING CO., LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| CN-100475518-C | Embossed release paper for production of synthetic leather, support thereof, synthetic leather utilizing the release paper and process for producing the same | DAINIPPON PRINTING CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| EP-1992479-A1 | ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING ORIGINAL SHEET OF EMBOSSED RELEASE SHEET, METHOD FOR PRODUCING EMBOSSED RELEASE SHEET, APPARATUS FOR PRODUCING EMBOSSED RELEASE SHEET, SYNTHETIC LEATHER, AND METHOD FOR PRODUCING SYNTHETIC LEATHER | Dainippon Printing Co., Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| US-20070116929-A1 | Embossed release paper for synthetic leather production and support therefor, and synthetic leather using the release paper and process for producing the synthetic leather | DAI NIPPON PRINTING CO., LTD. (JP) | 2007-05-24 | — | — | US | disclosed |
| CN-1922007-A | Embossed release paper for production of synthetic leather, support thereof, synthetic leather utilizing the release paper and process for producing the same | DAINIPPON PRINTING CO LTD (JP) | 2007-02-28 | — | — | CN | disclosed |
| EP-1702752-A1 | EMBOSSED RELEASE PAPER FOR PRODUCTION OF SYNTHETIC LEATHER, SUPPORT THEREOF, SYNTHETIC LEATHER UTILIZING THE RELEASE PAPER AND PROCESS FOR PRODUCING THE SAME | Dainippon Printing Co., Ltd. (JP) | 2006-09-20 | — | — | EP | disclosed |
| US-20030118838-A1 | Laminate, adhering method and active energy ray-curable composition | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1275496-A1 | LAYERED PRODUCT, BONDING METHOD, AND COMPOSITION CURABLE WITH ACTINIC ENERGY RAY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2003-01-15 | — | — | EP | disclosed |