Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23353832 | 0.89 | POLB (0.39) | POLBPTGS2DGAT1GRIN1GRIN2B | |
| SCHEMBL30989728 | 0.87 | POLB (0.39) | POLBGRM2DRD2DRD4DGAT1 | |
| SCHEMBL25885629 | 0.87 | POLB (0.39) | POLBGRM2DRD2DRD4DGAT1 | |
| SCHEMBL20386921 | 0.86 | POLB (0.43) | POLBGRM2PTGS2DRD2DRD4 | |
| SCHEMBL18737471 | 0.84 | POLB (0.38) | POLBGRM2DRD2DRD4MCHR1 | |
| SCHEMBL23353557 | 0.84 | POLB (0.39) | POLBGRM2DRD2DRD4GRIN1 | |
| SCHEMBL23353746 | 0.84 | DGAT1 (0.36) | POLBPTGS2DGAT1KCNH2PTGS1 | |
| SCHEMBL17844030 | 0.83 | POLB (0.43) | POLBGRM2DRD2DRD4MCHR1 | |
| SCHEMBL30711169 | 0.83 | POLB (0.43) | POLBGRM2DRD2DRD4MCHR1 | |
| SCHEMBL23353547 | 0.83 | POLB (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | POLB 4632/4885GRM2 1197/4885PTGS2 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.