Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21610551 | 0.84 | POLB (0.34) | POLBDRD2DRD4DRD3GRM2 | |
| SCHEMBL21609570 | 0.84 | POLB (0.38) | POLBPDE2ADRD2DRD3 | |
| SCHEMBL20386921 | 0.81 | POLB (0.43) | POLBPDE2ADRD2DRD4DRD3 | |
| SCHEMBL21609571 | 0.79 | POLB (0.46) | POLBPDE2A | |
| SCHEMBL23353737 | 0.77 | POLB (0.32) | POLB | |
| SCHEMBL23353561 | 0.77 | POLB (0.40) | POLBDRD2DRD4GRM2 | |
| SCHEMBL23353557 | 0.76 | POLB (0.39) | POLBDRD2DRD4DRD3GRM2 | |
| SCHEMBL23353832 | 0.76 | POLB (0.39) | POLB | |
| SCHEMBL19712048 | 0.75 | POLB (0.40) | POLB | |
| SCHEMBL17844030 | 0.75 | POLB (0.43) | POLBPDE2ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | POLB 4632/4885PDE2A 1367/4885DRD2 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.