SCHEMBL2335489

SCHEMBL2335489

Cc1ccc(S(=O)(=O)OCCN(CCOS(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
CNR2 P34972 6/20 0.47
NCF1 P14598 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
NPC1 O15118 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 1/20 0.43
MCOLN3 Q8TDD5 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
C5AR1 P21730 1/20 0.41
AGER Q15109 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6443129 0.98 GLA (0.49) GLACNR2NCF1SMN1; SMN2NPC1
SCHEMBL9593490 0.95 GLA (0.46) GLACNR2NCF1SMN1; SMN2NPC1
SCHEMBL15144440 0.94 CA9 (0.50) GLACNR2NCF1SMN1; SMN2NPC1
SCHEMBL9052348 0.88 GLA (0.40) GLACNR2NCF1SMN1; SMN2LMNA
SCHEMBL8751226 0.87 GLA (0.42) GLACNR2NCF1SMN1; SMN2L3MBTL1
SCHEMBL5441671 0.87 CNR2 (0.50) GLACNR2NCF1SMN1; SMN2NPC1
SCHEMBL3539599 0.86 MAPT (0.43) GLACNR2LMNAHTTMAPT
SCHEMBL3512796 0.86 MAPT (0.43) GLACNR2LMNAHTTMAPT
SCHEMBL3685046 0.85 HCRTR2 (0.44) SMN1; SMN2LMNARAB9AL3MBTL1CA12
SCHEMBL3691836 0.85 CNR2 (0.46) CNR2NCF1SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6187083-B1 INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER XEROX CORPORATION 2001-02-13 US claimed
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute 2025-06-05 US disclosed
EP-4452918-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2024-10-30 EP disclosed
US-20240190821-A1 SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF TRIANA BIOMEDICINES INC (US) 2024-06-13 US disclosed
WO-2024090531-A1 CATION-CURABLE COMPOSITION 日産化学株式会社 2024-05-02 WO disclosed
CN-117832615-A Functional additive, electrolyte and lithium-sulfur battery 江西微电新能源有限公司 2024-04-05 CN disclosed
WO-2023122276-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF Sanford Burnham Prebys Medical Discovery Institute (US) 2023-06-29 WO disclosed
US-20220081737-A1 POND REACTOR FOR RECOVERY OF METALS CYCAD GROUP, LLC 2022-03-17 US disclosed
US-20210340025-A1 Compositions and Methods for Purification of Metals from Steel Making Waste Streams CYCAD GROUP, LLC 2021-11-04 US disclosed
EP-3853177-A1 COMPOSITIONS AND METHODS FOR PURIFICATION OF METALS FROM STEEL MAKING WASTE STREAMS Lixivia, Inc. (US) 2021-07-28 EP disclosed
EP-0617028-A1 Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulfonyl piperazine U C B, S.A. (BE) 1994-09-28 EP disclosed
US-5322681-A Chelating compounds NYCOMED IMAGING AS (NO) 1994-06-21 US disclosed
EP-0287465-B1 CYCLIC LIGANDS CONTAINING NITROGEN, METAL COMPLEXES FORMED BY THESE LIGANDS, DIAGNOSTIC COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION GUERBET S.A. (FR) 1993-01-27 EP disclosed
EP-0499501-A2 New macrocyclic nitrogen ligands, method for their preparation, metal complexes, diagnostic and therapeutic compositions GUERBET S.A. (FR) 1992-08-19 EP disclosed
WO-1992012978-A1 NOVEL NITROGENOUS MACROCYCLIC LIGANDS, THEIR PREPARATION METHOD, POLYMETALLIC COMPLEXES, AND A DIAGNOSTIC AND THERAPEUTICAL COMPOSITION GUERBET S.A. (FR) 1992-08-06 WO disclosed
US-5049667-A Nitrogen-containing cyclic ligands GUERBET S.A. (FR) 1991-09-17 US disclosed
EP-0417671-A2 3,4,5,6-Tetrahydro-2H-1,7,4-Benzodioxazonines as cardiovascular agents BERLEX LABORATORIES, INC. (US) 1991-03-20 EP disclosed
US-4966967-A 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents BERLEX LABORATORIES, INC. (US) 1990-10-30 US disclosed
EP-0287465-A1 Cyclic ligands containing nitrogen, metal complexes formed by these ligands, diagnostic compositions containing them and process for their preparation GUERBET S.A. (FR) 1988-10-19 EP disclosed
US-4001279-A CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179000-A1 METABOTROPIC GLUTAMATE RECEPTOR POSITIVE ALLOSTERIC MODULATORS (PAMS) AND USES THEREOF GRM3, GRM2, GRM1 GLA 3953/4885CNR2 213/4885NCF1 3829/4885
US-20240190821-A1 SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL)BENZENESULFONAMIDES AND USES THEREOF PACSIN2, TPX2, PRSS12 GLA 2236/4885CNR2 2070/4885NCF1 388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.