SCHEMBL23355263

SCHEMBL23355263

CC1(C)CC(OC(=O)/C=C/C(=O)OC2CC(C)(C)N(O)C(C)(C)C2)CC(C)(C)N1O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.47
HTT P42858 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 2/20 0.33
ESR1 P03372 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALOX15 P16050 1/20 0.33
CYP2D6 P10635 1/20 0.31
LMNA P02545 1/20 0.31
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27033855 0.91 GAA (0.43) GAAHTTL3MBTL1TSHRKMT2A
SCHEMBL1053833 0.85 GAA (0.44) GAAHTTL3MBTL1TSHRKMT2A
SCHEMBL10707940 0.85 TSHR (0.35) GAAHTTTSHRKMT2AALDH1A1
SCHEMBL8790619 0.85 TSHR (0.35) GAAHTTTSHRKMT2AALDH1A1
SCHEMBL8790610 0.85 TSHR (0.35) GAAHTTTSHRKMT2AALDH1A1
SCHEMBL7526296 0.82 GAA (0.50) GAAHTTL3MBTL1TSHRKMT2A
SCHEMBL3765199 0.82 GAA (0.50) GAAHTTL3MBTL1TSHRKMT2A
SCHEMBL14632919 0.81 CYP2C19 (0.50) GAAHTTTSHRKMT2AALDH1A1
SCHEMBL22127756 0.80 GAA (0.49) GAAHTTL3MBTL1TSHRKMT2A
SCHEMBL241284 0.80 KMT2A (0.50) GAAHTTL3MBTL1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3820846-A1 COMPOSITION FOR INHIBITING MONOMER POLYMERIZATION COMPRISING A NITROXIDE INHIBITOR, A QUINONE METHIDE RETARDER AND AN AMINE STABILIZER Ecolab USA, Inc. (US) 2021-05-19 EP disclosed
CN-112533902-A Compositions comprising nitroxide inhibitors, quinone methide blockers and amine stabilizers to inhibit polymerization of monomers 埃科莱布美国股份有限公司 2021-03-19 CN disclosed