Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.73 |
| ▸ | KCNA3 | P22001 | 5/20 | 0.67 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788617 | 0.86 | MAOA (0.78) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL9184365 | 0.84 | MAOA (0.76) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL17373028 | 0.84 | MAOA (1.00) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL18788619 | 0.84 | MAOA (0.74) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL18788613 | 0.84 | MAOA (0.74) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL6709622 | 0.83 | MAOA (0.78) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL3446041 | 0.83 | MAOA (0.78) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL10491029 | 0.83 | MAOA (0.78) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL13985912 | 0.82 | MAOA (0.68) | MAOAKCNA3KCNA5CYP3A4CYP2D6 | |
| SCHEMBL8806449 | 0.81 | CYP3A4 (0.71) | MAOAKCNA3KCNA5CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157519-B1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | IMMUNOLIGHT LLC (US) | 2021-05-12 | — | — | EP | disclosed |