Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524946 | 0.79 | VSIR (0.40) | NPSR1SMN1; SMN2 | |
| SCHEMBL28519573 | 0.79 | BACE1 (0.37) | BACE1NPSR1SMN1; SMN2LMNANPC1 | |
| SCHEMBL28520028 | 0.78 | NPSR1 (0.49) | BACE1NPSR1TACR1ADORA2AADORA1 | |
| SCHEMBL2032508 | 0.78 | NPSR1 (0.51) | BACE1NPSR1SMN1; SMN2TACR1ADORA2A | |
| SCHEMBL4714046 | 0.77 | KCNH2 (0.36) | BACE1NPSR1IRAK4 | |
| SCHEMBL29529715 | 0.76 | KCNH2 (0.38) | BACE1NPSR1LMNATACR1IRAK4 | |
| SCHEMBL4715736 | 0.76 | KCNH2 (0.38) | BACE1NPSR1LMNATACR1IRAK4 | |
| SCHEMBL28516168 | 0.76 | NPSR1 (0.47) | BACE1NPSR1L3MBTL1NPC1RAB9A | |
| SCHEMBL12690863 | 0.73 | NPSR1 (0.47) | BACE1NPSR1RAB9ATACR1ADORA2A | |
| SCHEMBL4713936 | 0.73 | NQO2 (0.46) | NPSR1LMNAMAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820474-A1 | ADENOSINE RECEPTOR BINDING COMPOUNDS | Nikang Therapeutics, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |