Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355757 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL501841 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL2257304 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL30677181 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL20425363 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL28606425 | 0.86 | NPC1 (0.37) | KDM4EALDH1A1POLBL3MBTL1ALOX15 | |
| SCHEMBL26317865 | 0.86 | NPC1 (0.37) | KDM4EALDH1A1POLBL3MBTL1ALOX15 | |
| SCHEMBL7849736 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL7673144 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDMAPK1 | |
| SCHEMBL18639834 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3820532-A2 | DIMERIC IMMUNO-MODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS | H. Lee Moffitt Cancer Center & Research Institute, Inc. (US) | 2021-05-19 | — | — | EP | disclosed |