Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479938 | 0.98 | ALDH1A1 (0.63) | ALDH1A1EPHX1LMNAMEN1KMT2A | |
| SCHEMBL28480892 | 0.87 | ALDH1A1 (0.77) | ALDH1A1EPHX1LMNAMEN1KMT2A | |
| SCHEMBL11151764 | 0.82 | ALDH1A1 (0.69) | ALDH1A1EPHX1LMNAMEN1KMT2A | |
| SCHEMBL11042948 | 0.80 | ALDH1A1 (1.00) | ALDH1A1EPHX1LMNATP53SMN1; SMN2 | |
| SCHEMBL28935133 | 0.80 | ALDH1A1 (0.67) | ALDH1A1EPHX1FFAR1SMN1; SMN2KDM4E | |
| SCHEMBL6135606 | 0.79 | ALDH1A1 (0.66) | ALDH1A1EPHX1FFAR1TP53SMN1; SMN2 | |
| SCHEMBL13693493 | 0.78 | ALDH1A1 (0.65) | ALDH1A1EPHX1KMT2ASMN1; SMN2 | |
| SCHEMBL28087858 | 0.78 | ALDH1A1 (0.70) | ALDH1A1EPHX1LMNAMEN1KMT2A | |
| SCHEMBL1857831 | 0.78 | ALDH1A1 (0.65) | ALDH1A1EPHX1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11274069 | 0.78 | ALDH1A1 (0.96) | ALDH1A1EPHX1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247609-B2 | Aminoacid derivatives containing a disulfanyl group in the form of mixed disulfanyl and aminopeptidase N inhibitors | Pharamleads (FR) | 2012-08-21 | — | — | US | disclosed |
| EP-1940818-B1 | AMINOACID DERIVATIVES CONTAINING A DISULFANYL GROUP IN THE FORM OF MIXED DISULFANYL AND AMINOPEPTIDASE N INHIBITORS | PHARMALEADS (FR) | 2011-08-24 | — | — | EP | disclosed |