Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.57 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338132 | 0.93 | LPAR1 (0.57) | LPAR1LPAR3LPAR2DGAT1SOAT1 | |
| SCHEMBL2337558 | 0.93 | LPAR1 (0.55) | LPAR1LPAR3LPAR2DGAT1SOAT1 | |
| SCHEMBL2338268 | 0.91 | LPAR1 (0.68) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3714467 | 0.91 | LPAR1 (0.61) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3702336 | 0.90 | LPAR1 (0.60) | LPAR1LPAR3LPAR2DGAT1SCN9A | |
| SCHEMBL3704162 | 0.90 | LPAR1 (0.63) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3700613 | 0.88 | LPAR1 (0.61) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL2336526 | 0.88 | LPAR1 (0.55) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL2337111 | 0.87 | LPAR1 (0.55) | LPAR1LPAR3LPAR2PTGDR2KDM4E | |
| SCHEMBL2342594 | 0.87 | LPAR1 (0.55) | LPAR1LPAR3LPAR2SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358688-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077883-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |