SCHEMBL23356002

SCHEMBL23356002

Cn1ccc(O)c(C(=O)O)c1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
KDM4E B2RXH2 2/20 0.39
KDM6A O15550 1/20 0.39
KDM4A O75164 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM5C P41229 1/20 0.39
KDM2B Q8NHM5 1/20 0.39
DOHH Q9BU89 1/20 0.39
KDM2A Q9Y2K7 1/20 0.39
BRD4 O60885 1/20 0.36
TAF1 P21675 1/20 0.36
BRPF1 P55201 1/20 0.36
CREBBP Q92793 1/20 0.36
CECR2 Q9BXF3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27302249 0.79 KDM4E (0.39) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL12417622 0.79 BRD4 (0.42) CA12CA1CA2CA7CA9
SCHEMBL1400324 0.79 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL12809054 0.79 KDM4E (0.37) CA12CA1CA2CA7CA9
SCHEMBL28326993 0.78 BRD9 (0.35) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL17594820 0.76 CA12 (0.39) CA12CA1CA2CA7CA9
SCHEMBL31405408 0.75 CA12 (0.55) CA12CA1CA2CA7CA9
SCHEMBL27305850 0.75 LIPG (0.38) KDM4EKDM6AKDM4ACYP2C9CYP2C19
SCHEMBL5200415 0.74 CA12 (0.39) CA12CA1CA2CA7CA9
SCHEMBL12033675 0.74 KDM4E (0.47) KDM4EKDM6AKDM4ACYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3819300-A1 BIOMARKER-BASED THERAPEUTIC COMPOSITION Wellmarker Bio Co., Ltd. (KR) 2021-05-12 EP disclosed