Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.59 |
| ▸ | PNP | P00491 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.53 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | KRAS | P01116 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662102 | 0.86 | POLB (0.66) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL22930807 | 0.86 | POLB (0.55) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL21636994 | 0.84 | PNP (0.56) | POLGPNPPOLBTGM2HPRT1 | |
| Carbovir 5'-Triphosphate, (-)- SCHEMBL23391359 | 0.84 | POLG (0.56) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL15747215 | 0.83 | KRAS (0.56) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL18648306 | 0.83 | KRAS (0.56) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL22110609 | 0.83 | POLG (0.55) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL22110847 | 0.83 | POLG (0.55) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL20850301 | 0.83 | POLB (0.55) | POLGPNPPOLBFUT5TGM2 | |
| SCHEMBL22110836 | 0.83 | POLG (0.54) | POLGPNPPOLBFUT5TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202850-B2 | Cyclobutyl purine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2025-01-21 | — | — | US | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2023-09-21 | — | — | US | disclosed |
| EP-3831836-B1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORP (JP) | 2023-09-06 | — | — | EP | disclosed |
| EP-3831836-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM Corporation (JP) | 2021-06-09 | — | — | EP | disclosed |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-20 | — | — | US | disclosed |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295202-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | SLC28A1, SLC20A1, SLC29A1 | POLG 1150/4885PNP 48/4885POLB 141/4885 |
| US-20210147456-A1 | CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF | SLC28A1, SLC20A1, SLC29A1 | POLG 1150/4885PNP 48/4885POLB 141/4885 |
| US-12202850-B2 | Cyclobutyl purine derivative or salt thereof | SLC28A1, SLC20A1, SLC29A1 | POLG 1150/4885PNP 48/4885POLB 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.