Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | HBB | P68871 | 2/20 | 0.82 |
| ▸ | CASP1 | P29466 | 1/20 | 0.82 |
| ▸ | CASP7 | P55210 | 1/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.79 |
| ▸ | GLA | P06280 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | STAT6 | P42226 | 1/20 | 0.79 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | GMNN | O75496 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986960 | 1.00 | TOP1 (0.82) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28123033 | 0.99 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5723890 | 0.94 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18296582 | 0.93 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9749459 | 0.93 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8480542 | 0.93 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27463178 | 0.93 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL29225713 | 0.91 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18296774 | 0.91 | TOP1 (0.77) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7262395 | 0.91 | TOP1 (0.80) | TOP1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110193084-A | It is a kind of containing Polyvinylcaprolactame-polyvinyl acetate-polyethyleneglycol-graft copolymer pharmaceutical preparation and preparation method thereof | 付纪军 | 2019-09-03 | — | — | CN | claimed |
| CN-105884789-A | 10-fluorocamptothecin derivatives, and preparation method and application thereof | 兰州大学 | 2016-08-24 | — | — | CN | claimed |
| CN-102000080-A | Method for solubilizing camptothecin compound | EPITOMICS INC | 2011-04-06 | — | — | CN | claimed |
| CN-100567302-C | The preparation method of 7-ethyl-camptothecin | SHIRUI SCIENCE & TECHNOLOGY WU (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101074232-A | Production of 7-ethyl-camptothecin | SHIRUI SCIENCE & TECHNOLOGY WU (CN) | 2007-11-21 | — | — | CN | claimed |
| CN-1343209-A | Camptothecin having antitumor activity | SIGMA TAU IND FARMACEUTICHE S (IT) | 2002-04-03 | — | — | CN | claimed |
| US-12281301-B2 | Sequencing-based proteomics | THE BROAD INSTITUTE, INC. (US) | 2025-04-22 | — | — | US | disclosed |
| US-20210147831-A1 | SEQUENCING-BASED PROTEOMICS | THE BROAD INSTITUTE, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| CN-110193084-A | It is a kind of containing Polyvinylcaprolactame-polyvinyl acetate-polyethyleneglycol-graft copolymer pharmaceutical preparation and preparation method thereof | 付纪军 | 2019-09-03 | — | — | CN | disclosed |
| CN-109796462-A | A kind of preparation method of irinotecan hydrochloride | 辰欣药业股份有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-106727632-A | A kind of compound formulation for treating acute glomerulonephritis | 郑州仁宏医药科技有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106727883-A | It is a kind of to treat Chinese and Western medicine composite preparation of acute glomerulonephritis and preparation method thereof | 郑州仁宏医药科技有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106727883-A | It is a kind of to treat Chinese and Western medicine composite preparation of acute glomerulonephritis and preparation method thereof | 郑州仁宏医药科技有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-101080227-A | Combinations of therapeutic agents for treating cancer | NOVARTIS AG (CH) | 2007-11-28 | — | — | CN | disclosed |
| CN-101056619-A | Pharmaceutical compositions comprising a camtothecin derivate | NOVARTIS AG (CH) | 2007-10-17 | — | — | CN | disclosed |
| CN-1955183-A | 20-bit esterified camptothecine derivate, its preparation method and drug composite and use | MEDICAL INST CHINESE ACADEMY O (CN) | 2007-05-02 | — | — | CN | disclosed |
| CN-1660851-A | Ramification of water-soluble camptothecin and preparation method | DONGBEI FOREST UNIV (CN) | 2005-08-31 | — | — | CN | disclosed |
| CN-1139592-C | Camptothecin derivatives, their preparation and intermediates | ϣ��������ҩ��ҵ��˾ | 2004-02-25 | — | — | CN | disclosed |
| CN-1343209-A | Camptothecin having antitumor activity | SIGMA TAU IND FARMACEUTICHE S (IT) | 2002-04-03 | — | — | CN | disclosed |
| CN-1159192-A | Substituted camptothecin derivatives and process for their preparation | PHARMACIA & UPJOHN SPA (IT) | 1997-09-10 | — | — | CN | disclosed |