Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.77 |
| ▸ | HBB | P68871 | 2/20 | 0.77 |
| ▸ | CASP1 | P29466 | 1/20 | 0.77 |
| ▸ | CASP7 | P55210 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | STAT6 | P42226 | 1/20 | 0.74 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | GMNN | O75496 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225713 | 0.93 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7055883 | 0.93 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18296582 | 0.93 | TOP1 (0.79) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18296774 | 0.92 | TOP1 (0.77) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9749459 | 0.92 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL23358409 | 0.91 | TOP1 (0.82) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2986960 | 0.91 | TOP1 (0.82) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5723890 | 0.91 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL28123033 | 0.91 | TOP1 (0.81) | TOP1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8483773 | 0.90 | TOP1 (0.75) | TOP1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670899-A | Camptothecin compound nano drug delivery system and preparation method thereof | 湖州师范学院 | 2020-09-18 | — | — | CN | claimed |
| US-5942518-A | WATER SOLUBLE, LESS TOXIC ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | claimed |
| JP-8333371-A | — | — | None | — | — | JP | disclosed |
| CN-111670899-B | Camptothecin compound nano drug delivery system and preparation method thereof | 湖州师范学院 | 2021-09-24 | — | — | CN | disclosed |
| CN-111670899-A | Camptothecin compound nano drug delivery system and preparation method thereof | 湖州师范学院 | 2020-09-18 | — | — | CN | disclosed |
| EP-0861842-B1 | NOVEL WATER-SOLUBLE FLUOROETHYLCAMPTOTHECIN DERIVATIVE AND PROCESS FOR PRODUCTION THEREOF | KYORIN SEIYAKU KK (JP) | 2003-11-05 | — | — | EP | disclosed |
| CN-1058716-C | Novel water-soluble fluoroethylcamptothecin derivative and process for production thereof | KYORIN SEIYAKU KK (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1058716-C | Novel water-soluble fluoroethylcamptothecin derivative and process for production thereof | KYORIN SEIYAKU KK (JP) | 2000-11-22 | — | — | CN | disclosed |
| US-5942518-A | WATER SOLUBLE, LESS TOXIC ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5942518-A | WATER SOLUBLE, LESS TOXIC ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5942518-A | WATER SOLUBLE, LESS TOXIC ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| CN-1187195-A | Novel water-soluble fluoroethylcamptothecin derivative and process for production thereof | KYORIN SEIYAKU KK (JP) | 1998-07-08 | — | — | CN | disclosed |
| CN-1187195-A | Novel water-soluble fluoroethylcamptothecin derivative and process for production thereof | KYORIN SEIYAKU KK (JP) | 1998-07-08 | — | — | CN | disclosed |
| JP-H08333371-A | PRODUCTION OF OPTICALLY ACTIVE 4-(2-FLUOROETHYL) PYRANOINDOLIDINE DERIVATIVE | KYORIN PHARMACEUT CO LTD | 1996-12-17 | — | — | JP | disclosed |
| CN-1031941-C | Process for preparing fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-06-05 | — | — | CN | disclosed |
| CN-1031941-C | Process for preparing fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-06-05 | — | — | CN | disclosed |
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0471358-B1 | Fluoroethylcamptothecin derivatives | KYORIN SEIYAKU KK (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |
| EP-0471358-A1 | Fluoroethylcamptothecin derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-02-19 | — | — | EP | disclosed |