Glycerin

Glycerin

SCHEMBL2335853

C=C.C=C.OCC(O)CO

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.82
ALDH1A1 P00352 1/20 0.82
THRB P10828 1/20 0.50
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 1/20 0.33
OR51E2 Q9H255 1/20 0.32
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL21988052 1.00 LMNA (0.82) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL334464 1.00
Glycerin SCHEMBL9130517 1.00 LMNA (0.82) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL2305273 1.00 LMNA (0.82) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL3725402 1.00 LMNA (0.82) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL27710119 0.96
Glycerin SCHEMBL10457130 0.92 LMNA (0.69) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL11352453 0.92 LMNA (0.69) LMNAALDH1A1THRBTDP1L3MBTL1
Glycerin SCHEMBL797 0.91
Glycerin SCHEMBL5610362 0.91 LMNA (1.00) LMNAALDH1A1THRBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024015959-A1 METHODS OF MAKING AND USING CONTACT LENSES INCLUDING MEDICAMENTS AND STABILIZERS OF LABILE COMPONENTS SUCH AS DRUGS DOSHI PRAFUL (US) 2024-01-18 WO disclosed
US-20220218600-A1 MEDICAL DEVICES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING ENHANCING COMFORT, ENHANCING DRUG PENETRATION, AND TREATMENT OF MYOPIA MEDIPRINT OPHTHALMICS INC. 2022-07-14 US disclosed
US-11234927-B2 Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia MEDIPRINT OPHTHALMICS INC. 2022-02-01 US disclosed
US-20210346285-A1 MEDICAL DEVICES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING ENHANCING COMFORT, ENHANCING DRUG PENETRATION, AND TREATMENT OF MYOPIA MEDIPRINT OPHTHALMICS INC. 2021-11-11 US disclosed
US-11077054-B2 Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia MEDIPRINT OPHTHALMICS INC. 2021-08-03 US disclosed
US-20210163668-A1 ELECTROACTIVE POLYMERS BASF SE (DE) 2021-06-03 US disclosed
US-20210038509-A1 MEDICAL DEVICES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING ENHANCING COMFORT, ENHANCING DRUG PENETRATION, AND TREATMENT OF MYOPIA MEDIPRINT OPHTHALMICS INC. 2021-02-11 US disclosed
EP-3039074-B1 BLOW MOLDING METHOD FOR FORMING CONTAINERS USING A HIGHLY MODIFIED POLYESTERS DISCMA AG (CH) 2020-12-02 EP disclosed
US-10842740-B2 Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia MEDIPRINT OPHTHALMICS INC. 2020-11-24 US disclosed
US-20200268649-A1 MEDICAL DEVICES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING ENHANCING COMFORT, ENHANCING DRUG PENETRATION, AND TREATMENT OF MYOPIA MEDIPRINT OPHTHALMICS INC. 2020-08-27 US disclosed
US-20030009949-A1 Abrasive article with optimally oriented abrasive particles and method of making the same 3M INNOVATIVE PROPERTIES COMPANY 2003-01-16 US disclosed
WO-2002068154-A1 ABRASIVE ARTICLE WITH OPTIMALLY ORIENTED ABRASIVE PARTICLES AND METHOD OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2002-09-06 WO disclosed
US-20020030788-A1 Tinted lenses and methods of manufacture DOSHI PRAFUL (US) 2002-03-14 US disclosed
US-6315410-B1 Tinted lenses and methods of manufacture DOSHI, PRAFUL 2001-11-13 US disclosed
US-5158832-A Lenses from polymeric derivatives of acrylic and methacrylic acids CESKOSLOVENSKA AKADEMIE VED (CS) 1992-10-27 US disclosed
US-5021263-A Whole or partial etherified 1,3-dialkyl-4,5-dihydroxy-imidazolidinone; shrink resistace CIBA-GEIGY CORPORATION (US) 1991-06-04 US disclosed
US-4478894-A ISOCYANATE COMPONENT IS OXADIAZINETRIONE RING FROM REACTION OF BISISOCYANATOMETHYL/CYCLOHEXANE AND CARBON DIOXIDE TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1984-10-23 US disclosed
US-4346185-A Process for the production of alkali metal unsaturated polyester silicate resinous products BLOUNT DAVID H 1982-08-24 US disclosed
US-4293480-A Urethane binder compositions for no-bake and cold box foundry application utilizing isocyanato-urethane polymers ASHLAND OIL, INC. (US) 1981-10-06 US disclosed
US-4110286-A Stable polyurethane latices, emulsifiable prepolymers therefor and methods of making the same ALCOLAC INC. (US) 1978-08-29 US disclosed