SCHEMBL23360706

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30168920	1.00	MAPT (0.54)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL19623582	0.91	MAPT (0.52)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL4461076	0.86	ALDH1A1 (0.50)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL24196353	0.86	ALDH1A1 (0.50)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL21032108	0.83	MAPT (0.47)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL24179133	0.83	MAPT (0.47)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL5327311	0.82	MAPK1 (0.55)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL19170774	0.82	ALDH1A1 (0.51)	MAPTLGMNHPGDTSHRNPSR1
	SCHEMBL11439640	0.80	ALDH1A1 (0.56)	MAPTNPSR1GAASMN1; SMN2ALDH1A1
	SCHEMBL21001151	0.80	MAPT (0.71)	MAPTNPSR1GAASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.