Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23349424 | 0.88 | SCD (0.38) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL141413 | 0.87 | FFAR1 (0.52) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL23360827 | 0.83 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL24920359 | 0.81 | ROCK2 (0.36) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL25826104 | 0.81 | FFAR1 (0.44) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL19341509 | 0.81 | FFAR1 (0.44) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL18202880 | 0.80 | FFAR1 (0.43) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL20733996 | 0.80 | FFAR1 (0.45) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL19672040 | 0.79 | FFAR1 (0.44) | FFAR1USP30ROCK2SCDNR1H2 | |
| SCHEMBL19964091 | 0.78 | FFAR1 (0.40) | FFAR1USP30ROCK2SCDNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021093795-A1 | ROCK INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 武汉朗来科技发展有限公司 | 2021-05-20 | — | — | WO | disclosed |
| CN-103080101-A | Piperidinyl-substituted lactams as GPR119 modulators | ARRAY BIOPHARMA INC | 2013-05-01 | — | — | CN | disclosed |