⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17225094 | 0.94 | — | — | |
| SCHEMBL30250687 | 0.94 | — | — | |
| SCHEMBL112 | 0.94 | — | — | |
| SCHEMBL27575648 | 0.94 | TSHR (0.39) | — | |
| SCHEMBL3882845 | 0.88 | — | — | |
| SCHEMBL11198303 | 0.88 | TSHR (0.36) | — | |
| Phosphine SCHEMBL11897664 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL649123 | 0.88 | — | — | |
| SCHEMBL17710801 | 0.88 | — | — | |
| SCHEMBL28837695 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111132979-B | Benzoxazinone derivatives as herbicides | 瑞戴格作物保护公司 | 2024-03-26 | — | — | CN | disclosed |
| US-RE48150-E1 | Apoptosis signal-regulating kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| CN-108033930-A | A kind of synthesis technique of Dasatinib analog | 湖北广辰药业有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-107148409-A | Substituted bicyclic compounds | 百时美施贵宝公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-106749425-A | Four new tooth platinum complexs | 通用显示公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2403860-B1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE AS HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS INC (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-2588475-B1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8927582-B2 | Apoptosis signal-regulating kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130203819-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-8440665-B2 | Apoptosis signal-regulating kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| EP-2283001-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| US-20100233123-A1 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-09-16 | — | — | US | disclosed |
| WO-2010101967-A2 | PHOSPHOTHIOPHENE AND PHOSPHOTHIAZOLE HCV POLYMERASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-09-10 | — | — | WO | disclosed |
| WO-2009140089-A2 | SULFONE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |
| EP-0994874-A1 | THIADIAZOLYL AND OXADIAZOLYL PHENYL OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002525-A1 | THIADIAZOLYL AND OXADIAZOLYL PHENYL OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
| CN-1036996-C | Method for preparing 3S,4R-N-oxalyl-3-ethyl-4-[1R-oxo-3S-thiolanylthio (thiocarbonyl)-thio]-2-azetidinones | PFIZER (US) | 1998-01-14 | — | — | CN | disclosed |
| CN-1023016-C | Diastereomeric 5R, 6S-6- (1R-hydroxyethyl) -2- (cis-1-oxo-3-thiacyclopentylthio) -2-penem-3-carboxylic acids | PFIZER (US) | 1993-12-08 | — | — | CN | disclosed |
| CN-1073442-A | Process for the preparation of (1R-oxo-3S-thienylpentylthio (thiocarbonyl) -thio) -2-azetidinones | PFIZER (US) | 1993-06-23 | — | — | CN | disclosed |
| CN-88102863-A | Diastereomeric 5R, 6S, -6- (1R-hydroxyethyl) -2, (cis-1-oxo-3-thiacyclopentylthio) -2-penem-3-carboxylic acids | — | 1988-12-21 | — | — | CN | disclosed |