Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23365093 | 0.97 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL23365104 | 0.97 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL23365035 | 0.97 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL340593 | 0.78 | — | — | |
| SCHEMBL23365089 | 0.77 | TSHR (0.39) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL23365107 | 0.74 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL19970584 | 0.74 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL19970595 | 0.74 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL23365053 | 0.74 | TSHR (0.37) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL5150115 | 0.74 | TSHR (0.44) | TSHRTHRBLMNASLC22A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220403056-A1 | CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS | BRIDGESTONE CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4058487-A2 | CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS | BRIDGESTONE CORPORATION (JP) | 2022-09-21 | — | — | EP | disclosed |
| WO-2021097455-A2 | CURED RUBBER NETWORK WITH COVALENT AND HYDROGEN-BONDED CROSSLINKS | BRIDGESTONE CORPORATION (JP) | 2021-05-20 | — | — | WO | disclosed |