Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525325 | 1.00 | HTR2A (0.38) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL8767567 | 0.98 | HTR2A (0.39) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL17827776 | 0.92 | HTR2A (0.42) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL10043153 | 0.92 | OPRL1 (0.41) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL8768461 | 0.89 | OPRL1 (0.39) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL8768472 | 0.89 | OPRL1 (0.39) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL10043342 | 0.89 | ABCB1 (0.38) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL8768466 | 0.89 | OPRL1 (0.39) | HTR2AHTR2CHTR2BUSP5HDAC6 | |
| SCHEMBL127034 | 0.88 | ACMSD (0.44) | HTR2AHTR2CHTR2BKMT2AACMSD | |
| SCHEMBL19850903 | 0.86 | KMT2A (0.39) | MEN1KMT2ANPC1RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008514-B2 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2021-05-18 | — | — | US | disclosed |