SCHEMBL23366193

SCHEMBL23366193

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nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 12/20 0.44
PRSS1 P07477 4/20 0.35
TMPRSS15 P98073 4/20 0.35
TGFBR1 P36897 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24136500 1.00 ENPEP (0.44) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL15027040 1.00 ENPEP (0.44) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL23366202 1.00 ENPEP (0.44) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL23366216 1.00 ENPEP (0.44) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL23366231 1.00 ENPEP (0.44) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL24136489 0.96 ENPEP (0.46) ENPEPPRSS1TMPRSS15TGFBR1
SCHEMBL7897829 0.83 ACE (0.45) ENPEP
SCHEMBL23366206 0.82 ENPEP (0.40) ENPEPPRSS1TMPRSS15
SCHEMBL23366240 0.82 ENPEP (0.40) ENPEPPRSS1TMPRSS15
SCHEMBL23366203 0.82 ENPEP (0.40) ENPEPPRSS1TMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11007274-B2 Compounds for medicinal applications AusVir Therapeutics Pty Ltd (AU) 2021-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11007274-B2 Compounds for medicinal applications HAVCR2, ENGASE, DNPEP ENPEP 69/4885PRSS1 459/4885TMPRSS15 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.